to compare the effect of intrathecal 0.5% hyperbaric bupivacaine 16mg over 0.5% hyperbaric bupivacaine 16mg + 5µg dexmedetomidine with respect to haemodynamic changes

Abstract

Introduction: Hyperbaric bupivacaine is commonly used as local anaesthetic for administering spinal anaesthesia. Spinal anaesthesia using local anaesthetic alone is associated with relatively short duration of action. Adjuvants are added to improve the quality, to accelerate the onset of action, prolong analgesia and to overcome the problems of spinal anaesthesia. Hypothesis: To compare the effect of intrathecal 0.5% Hyperbaric Bupivacaine 16mg over 0.5% Hyperbaric Bupivacaine 16mg + 5μg Dexmedetomidine with respect to Haemodynamic changes. Sample Size: We conducted the study on 60 patients over a period of one year and six months from 1 March 2016 to 31 August 2017. Results: Our study show that supplementation of spinal bupivacaine with 5 microgram dexmedetomidine resulted in stable hemodynamics. There was no significant decrease in the mean heart rate in dexmedetomidine group when compared to bupivacaine alone group. Conclusion: Our study showed that there was no significant decrease in the mean heart rate in dexmedetomidine group when compared to bupivacaine alone group.