Comparative enzyme histochemistry of different histo compartments of GALT of porcine

Abstract

Gut-associated lymphoid tissue (GALT) in pig comprises of Peyer’s patches (PP) in the small intestine and solitary lymphoid nodules (SLN) in the large intestine. GALT is responsible for protecting the gut mucosa from invasion of pathogenic microbes, toxins etc. thereby playing an important role in maintaining gut health. Different enzymes are involved in the process of antigen uptake, sampling and subsequent processing of gut luminal antigen by different components of the GALT and detection of the same may be indicative of the status of proper functioning of the GALT. The general organization pattern of GALT of the small and large intestine is different in terms of histocompartments; hence the presence of Histoenzymes might also differ. Sufficient literature is not available on the difference in the histoenzyme profile of GALT of small and large intestine. Therefore, the present investigation was attempted to elucidate the difference in histoenzyme profile of GALT in small and large intestine.