Assessment of levels of calprotectin levels in cervicular fluid from implant sites with peri implant pathogenesis

Abstract

Introduction: Peri-implant crevicular fluid (PICF) contains calprotectin, which are markers for inflammation and bone resorption, respectively. The aims of this study were to assessment of levels of calprotectinlevelsincervicular fluid from implant sites with peri implant pathogenesis.in PICF from implant sites with peri-implant diseases and to evaluate the usefulness of calprotectin diagnostic markers for peri-implant diseases. Methods: 90 patients with dental implants participated in this study. PICF samples were collected from peri-implant disease sites (n=50) and non-diseased (healthy) sites (n=40) after clinical indicators including probing depth (PD), bleeding on probing (BOP), gingival index (GI), and bone loss (BL) rate were investigated. Calprotectin amounts in PICF were measured using their respective ELISA kits and then compared between diseased and healthy samples. The relationship between PICF calprotectinand levels and clinical indicator levels was investigated. Results: Calprotectin levels in PICF were significantly higher from peri-implant disease sites than from healthy sites. Conclusions: Calprotectin levelsin PICF have potential as biomarkers for the diagnosis of peri-implant diseases.