Analysis of the performance of the ultra-diluted Viscum album in cultivation of mesenchymal stem cells and mammary adenocarcinoma cells pmc-42 and mcf-7

Abstract

Adenocarcinoma in breast can be of several types and PMC-42 and MCF-7 cell lines are a well-established cell lines used in in vitro studies retaining much of the breast's native phenotype. Viscum album, a plant which extract has cytotoxic effects, is included in the brand-new class of cancer therapies and its ultra-diluted version is a promising area of interest. The MTT assay was realized to evaluate the cytotoxic potential and calculate the inhibitory concentration of different concentrations of ultra-diluted Viscum album D30 (VAD30). The results indicated that 60mL/mL, 37mL/mL and 35ml/mL of VAD30 were cytotoxic to 50% of mesenchymal stem cell, MCF-7 and PMC-42 cells respectively. This result shows the better potency of action of VAD30 against tumor cells, as a lower concentration inhibits the growing of this cell line in comparison to health cells, demonstrating that this medicine has the potential to be used in cancer therapy.