Correlation between presence of nocturnal oxygen desaturation with pulmonary hypertension

Abstract

Aim of the study: To study presence of nocturnal oxygen desaturation with pulmonary hypertension. Results: The mean age of patients was 69.51 years. The mean duration of COPD was 4.14 years. The mean smoking index of study population was 401.32. Mean baseline SPO2. The mean BMI was 26.32 kg/m2. The mean hemoglobin level was 11.21 g/dL. The partial pressure of oxygen and carbon dioxide in desaturators and nondesaturators was 61.54 mmHg and 70.65 mmHg respectively. The presence of nocturnal hypoxemia has been postulated as the etiopathological factor resulting in the development of pulmonary hypertension in COPD patients. Conclusion: From the results of the present study, this can be concluded that 29 % of the normoxemic patients had significant nocturnal desaturation. The significant predictors of nocturnal desaturation are PaO2 and PaCO2.