Clinical and biochemical profile in adolescent and adult polycystic ovary syndrome patients

Abstract

This study was conducted on 100 adolescent (11-19 years) and 100 adult (20-35 years) PCOS patients attending gynaecology outdoor at PGIMS Rohtak to compare clinical and biochemical profile in two groups. On comparing, it was found that most of the clinical parameters (heavy menstrual bleeding- 9% vs 2%, weight gain- 38% vs 24%, hirsutism- 58% vs 47%, BMI- 36% vs 17%) and biochemical parameters (increased LH/FSH ratio- 51% vs 41%, serum testosterone- 44% vs 33%) were deranged more in adults as compared to adolescents whereas parameters like oligomenorrhoea (87% vs 88%), acne (44% vs 46%), acanthosis nigricans (9% vs 8%), triglycerides (19% vs 18%) were comparable in both the groups. It was incidentally noticed that age of menarche is decreasing in Indian population (13.46±1.24 vs 13.83±1.05 -adolescents vs adults). Hence, early detection and treatment is needed for the better outcome.