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Predicting Infectious Severe Acute Respiratory Syndrome Coronavirus 2 From Diagnostic Samples
Clinical Infectious Diseases · 2020 · Vol. 71(10) · pp. 2663–2666
Jared Bullard✉(Manitoba Health)Kerry Dust(Manitoba Health)Duane J. Funk(Public Health Agency of Canada)James E. Strong(University of Manitoba)David C. Alexander(University of Manitoba)Lauren Garnett(University of Manitoba)Carl Boodman(University of Manitoba)Alexander Bello(University of Manitoba)Adam Hedley(Manitoba Health)Zachary Schiffman(Public Health Agency of Canada)Kaylie Doan(Public Health Agency of Canada)Nathalie Bastien(Public Health Agency of Canada)Yan Li(University of Manitoba)Paul G Van Caeseele(University of Manitoba)Guillaume Poliquin(Public Health Agency of Canada)
Abstract
SARS-CoV-2 Vero cell infectivity was only observed for RT-PCR Ct < 24 and STT < 8 days. Infectivity of patients with Ct > 24 and duration of symptoms > 8 days may be low. This information can inform public health policy and guide clinical, infection control, and occupational health decisions. Further studies of larger size are needed.
SARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologyInfectivityVero cellVirologyInterquartile rangeCoronavirusMedicineViral cultureViral loadOdds ratioConfidence interval
MeSH terms
COVID-19SARS-CoV-2AnimalsChlorocebus aethiopsCross-Sectional StudiesHumansRetrospective StudiesRNA, ViralVero Cells
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1,194
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28.83
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8
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Cited by
Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance
The Lancet Infectious Diseases · 2020 · 928 citations
References
Temporal dynamics in viral shedding and transmissibility of COVID-19
Nature Medicine · 2020 · 4,649 citations
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