A -Keto ester as a novel, efficient, and versatile ligand for copper (II)-catalyzed C-C coupling reactions and evaluation anti-bacterial activity

Abstract

Employing α-acetyl-γ-butyrolactone as a novel, efficient, and versatile ligand, the copper catalyzed Sonogashira and Suzuki coupling reactions with nucleophilic reagents with aryl halides and boronic acid could be successfully carried out under mild conditions. Synthesis. Present communication describes Synthesis, Characterization and IR spectrum, elemental analysis, mass spectrum, molar conductance, TGA and DTA analysis, catalytic activity, crystal structure with the help of single XRD and antimicrobial activity of Cu(II) complex.