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Synthesis of 2,4,5-Triaryl- 1H-imidazole derivatives using SiO2-NaHSO4
International Journal of Chemical Studies · 2020 · Vol. 8(2) · pp. 2417–2418
Abstract
A mixture of benzyl, aromatic aldehyde and ammonium acetate in presence of SiO2-NaHSO4 under solvent-free condition converted to 2,4,5-Triaryl-1H-Imidazoles. The short reaction time, cleaner reaction, and easy workup make this protocol practical and economically attractive.
Multicomponent Synthesis of HeterocyclesSynthesis and biological activityMicrowave-Assisted Synthesis and ApplicationsAmmonium acetateImidazoleAldehydeChemistryOrganic chemistrySolventCatalysisHigh-performance liquid chromatography
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