Menstrual disorders in chronic kidney disease: causes and management

Abstract

Chronic kidney disease is increasing in prevalence throughout the world. This leads to many hormonal changes in the body which in turn lead to variations in the menstrual bleeding patterns in premenopausal women. Dysfunction of the coagulation pathway is also seen with women developing either thrombotic tendency or bleeding disorder. This review paper examines the causative mechanisms of the endocrinological and bleeding disorders in kidney diseases. Decrease in kidney function affects the metabolism and excretion of medication used for treating these problems. The treatment modalities available for treatment of heavy menstrual bleeding in women suffering from chronic kidney ailments have been discussed to enable the treating physician to choose from options available to decrease the morbidity due to heavy menstrual bleeding and improve the quality of life.