Clinical outcome of post thrombotic syndrome in lower limbs treated by a novel method

Abstract

Background: Post-thrombotic syndrome (PTS) is a chronic and frequent complication of acute proximal DVT, affecting approximately half of patients within the first 1–2 years. Symptoms vary from mild oedema to chronic pain and ulceration. Severe PTS occurs in 5–10% of all symptomatic DVTs, and may lead to venous ulceration. PTS results in significant disability and impaired quality of life [5] and has a substantial healthcare cost [6]. Recent research has demonstrated that patients with PTS have a poorer quality of life. The signs and symptoms of PTS vary from patient to patient and may include edema, heaviness, leg pain, eczema, hyperpigmentation, lipodermatosclerosis, and venous ulcers.Methods: Five patients who were diagnosed as PTS were treated in the orthopaedic department with the help of PRP injection locally. The outcomes were measured and documented with the help of villalta score. Results: All the patients were followed up for a minimal period of 3 months. The VILLALTA score improved considerably in all the patients and the patients were symptomatically better. The majority of the improvement was seen in the swelling and pain which reduced considerably after the infiltration of PRP. The VILLALTA SCORES after infiltration were 6 in one patient and,