Serum retinol level in patients with Atopic dermatitis

Abstract

Introduction: Atopic dermatitis (AD) is a common dermatological disorder causing significant morbidity and manifested by diffuse symmetrical eczematous eruption. The present study assessed serum retinol level in patients with Atopic dermatitis. Materials & Methods: The present study was conducted on 74 cases of Atopic dermatitis of both genders. Equal number of control was also included. Serum retinol levels were assayed using a reversed‑phase high‑performance liquid chromatography (HPLC) method. Results: Out of 74 subjects, males were 32 and females were 42. The mean retinol level in group I subjects was 51.6 ng/g and in group II was 172.3 ng/g. The difference was significant (P< 0.05). Conclusion: Authors found that serum retinol level in patients of atopic dermatitis was significantly reduced as compared to healthy subjects.