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CRISPR–Cas12-based detection of SARS-CoV-2

Nature Biotechnology · 2020 · Vol. 38(7) · pp. 870–874
James P. BroughtonXianding DengGuixia YuClare L. FaschingVenice ServellitaJasmeet SinghXin MiaoJessica StreithorstAndrea GranadosAlicia Sotomayor-GonzálezKelsey C. ZornAllan GopezElaine HsuWei GuSteve MillerChao‐Yang PanHugo GuevaraDebra A. WadfordJanice S. ChenCharles Y. Chiu
CRISPR and Genetic EngineeringSARS-CoV-2 and COVID-19 ResearchMosquito-borne diseases and controlOutbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)CRISPRBetacoronavirusPandemic2019-20 coronavirus outbreakMedicineInfection control

MeSH terms

BetacoronavirusCOVID-19SARS-CoV-2COVID-19 VaccinesCOVID-19 TestingRNA, Guide, CRISPR-Cas SystemsHumansPneumonia, ViralTime FactorsRNA, Guide, KinetoplastidaCoronavirus InfectionsClinical Laboratory TechniquesNucleic Acid Amplification TechniquesPandemicsCRISPR-Cas Systems

Funding

  • Division of Intramural Research, National Institute of Allergy and Infectious Diseases
  • Charles and Helen Schwab Foundation
  • National Institutes of Health
  • National Heart, Lung, and Blood Institute
  • National Institute of Allergy and Infectious Diseases
Citations
2,715
FWCI
166.28
field-weighted impact
References
28
Percentile
100%
vs. same field & year
Citations per year
Cited by
Coronavirus Disease 2019–COVID-19
Clinical Microbiology Reviews · 2020 · 1,850 citations
References
Loop-mediated isothermal amplification of DNA
Nucleic Acids Research · 2000 · 8,626 citations
A novel coronavirus outbreak of global health concern
The Lancet · 2020 · 8,079 citations
A Novel Coronavirus from Patients with Pneumonia in China, 2019
New England Journal of Medicine · 2020 · 30,188 citations
First Case of 2019 Novel Coronavirus in the United States
New England Journal of Medicine · 2020 · 6,361 citations
Viral load of SARS-CoV-2 in clinical samples
The Lancet Infectious Diseases · 2020 · 1,704 citations
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CRISPR–Cas12-based detection of SARS-CoV-2 · Scinovex