article Open AccessTop 1% cited
Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province, China, January-March 2020: retrospective cohort study
BMJ · 2020 · Vol. 369 · pp. m1443–m1443
Shufa Zheng✉(State Key Laboratory of Diagnosis and Treatment of Infectious Diseases)Jian‐Gao Fan(Zhejiang University)Fei Yu(Zhejiang University)Baihuan Feng(Zhejiang University)Bin Lou(Zhejiang University)Qianda Zou(Zhejiang University)Guoliang Xie(Zhejiang University)Sha Lin(Zhejiang University)Ruonan Wang(Zhejiang University)Xianzhi Yang(Zhejiang University)Weizhen Chen(Zhejiang University)Qi Wang(Zhejiang University)Dan Zhang(Zhejiang University)Yanchao Liu(Zhejiang University)Renjie Gong(Zhejiang University)Zhaohui Ma(Zhejiang University)Siming Lu(Zhejiang University)Yanyan Xiao(Zhejiang University)Yaxi Gu(Zhejiang University)Jinming Zhang(Zhejiang University)Hangping Yao(State Key Laboratory of Diagnosis and Treatment of Infectious Diseases)Kaijin Xu(State Key Laboratory of Diagnosis and Treatment of Infectious Diseases)Xiaoyang Lu(Zhejiang University)Guoqing Wei(Zhejiang University)Jianying Zhou(Zhejiang University)Qiang Fang(Zhejiang University)Hongliu Cai(Zhejiang University)Yunqing Qiu(State Key Laboratory of Diagnosis and Treatment of Infectious Diseases)Jifang Sheng(State Key Laboratory of Diagnosis and Treatment of Infectious Diseases)Yu Chen(State Key Laboratory of Diagnosis and Treatment of Infectious Diseases)Tingbo Liang(First Affiliated Hospital Zhejiang University)
Abstract
The duration of SARS-CoV-2 is significantly longer in stool samples than in respiratory and serum samples, highlighting the need to strengthen the management of stool samples in the prevention and control of the epidemic, and the virus persists longer with higher load and peaks later in the respiratory tissue of patients with severe disease.
SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCOVID-19 epidemiological studiesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Retrospective cohort studyMedicineChina2019-20 coronavirus outbreakViral loadCohortDiseaseSars virus
MeSH terms
BetacoronavirusCOVID-19SARS-CoV-2AdultChinaFemaleHumansMaleMiddle AgedPneumonia, ViralRetrospective StudiesSeverity of Illness IndexCoronavirus InfectionsViral LoadPandemics
Funding
- National Natural Science Foundation of China
Citations
1,586
FWCI
37.39
field-weighted impact
References
40
Percentile
100%
vs. same field & year
Citations per year
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References
A Novel Coronavirus from Patients with Pneumonia in China, 2019
New England Journal of Medicine · 2020 · 30,188 citations
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
The Lancet · 2020 · 9,576 citations
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
New England Journal of Medicine · 2020 · 17,893 citations
Consistent Detection of 2019 Novel Coronavirus in Saliva
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Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
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