article Open AccessTop 1% cited
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
Cell · 2020 · Vol. 181(5) · pp. 1036–1045.e9
Daniel Blanco-Melo✉(Icahn School of Medicine at Mount Sinai)Benjamin E. Nilsson-Payant(Icahn School of Medicine at Mount Sinai)Wen‐Chun Liu(Icahn School of Medicine at Mount Sinai)Skyler Uhl(Icahn School of Medicine at Mount Sinai)Daisy A. Hoagland(Icahn School of Medicine at Mount Sinai)Rasmus Møller(Icahn School of Medicine at Mount Sinai)Tristan X. Jordan(Icahn School of Medicine at Mount Sinai)Kohei Oishi(Icahn School of Medicine at Mount Sinai)Maryline Panis(Icahn School of Medicine at Mount Sinai)David Sachs(Icahn School of Medicine at Mount Sinai)Taia T. Wang(Stanford University)Robert E. Schwartz(Weill Cornell Medicine)Jean K. Lim(Icahn School of Medicine at Mount Sinai)Randy A. Albrecht(Icahn School of Medicine at Mount Sinai)Benjamin R. tenOever(Icahn School of Medicine at Mount Sinai)
SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studiesinterferon and immune responsesBiologyChemokineImmunologyPandemicVirologyCoronavirus disease 2019 (COVID-19)Innate immune systemSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Ex vivoInflammatory response
MeSH terms
BetacoronavirusCOVID-19SARS-CoV-2AnimalsCells, CulturedDisease Models, AnimalHumansImmunity, InnateInflammationInterferonsPneumonia, ViralRNA VirusesTranscription, GeneticCoronavirus InfectionsChemokines
Funding
- National Institutes of Health
- Defense Advanced Research Projects Agency
- U.S. Public Health Service
- National Institute of Allergy and Infectious Diseases
Citations
4,475
FWCI
98.70
field-weighted impact
References
60
Percentile
100%
vs. same field & year
Citations per year
Cited by
Synergistic effect of remdesivir and pegylated interferon alfa 1 beta in treatment of Covid 19
International Journal of Advanced Research in Medicine · 2021 · 0 citations
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Nature reviews. Immunology · 2020 · 2,572 citations
Immune Response, Inflammation, and the Clinical Spectrum of COVID-19
Frontiers in Immunology · 2020 · 750 citations
The T cell immune response against SARS-CoV-2
Nature Immunology · 2022 · 1,295 citations
Immunology of COVID-19: Current State of the Science
Immunity · 2020 · 1,775 citations
Coronavirus biology and replication: implications for SARS-CoV-2
Nature Reviews Microbiology · 2020 · 3,331 citations
References
Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems
Virology · 1998 · 1,000 citations
Innate Immune Recognition
Annual Review of Immunology · 2002 · 8,305 citations
Fast gapped-read alignment with Bowtie 2
Nature Methods · 2012 · 59,710 citations
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Genome biology · 2014 · 97,164 citations
SARS and MERS: recent insights into emerging coronaviruses
Nature Reviews Microbiology · 2016 · 3,707 citations
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
Nucleic Acids Research · 2018 · 18,843 citations
Origin and evolution of pathogenic coronaviruses
Nature Reviews Microbiology · 2018 · 5,807 citations
A Novel Coronavirus from Patients with Pneumonia in China, 2019
New England Journal of Medicine · 2020 · 30,188 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.