article Open AccessTop 1% cited
Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
Nature Nanotechnology · 2020 · Vol. 15(4) · pp. 313–320
Qiang Cheng✉(The University of Texas Southwestern Medical Center)Tuo Wei(The University of Texas Southwestern Medical Center)Lukas Farbiak(The University of Texas Southwestern Medical Center)Lindsay T. Johnson(The University of Texas Southwestern Medical Center)Sean A. Dilliard(The University of Texas Southwestern Medical Center)Daniel J. Siegwart(Southwestern Medical Center)
RNA Interference and Gene DeliveryCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesCRISPRCas9RibonucleoproteinGenome editingMessenger RNABiologyRNAComputational biologyGeneCell biology
MeSH terms
Gene EditingAnimalsOrgan SpecificityRNA, MessengerDrug Delivery SystemsMiceNanoparticlesCRISPR-Cas Systems
Funding
- National Institute of Biomedical Imaging and Bioengineering
Citations
2,043
FWCI
71.42
field-weighted impact
References
56
Percentile
100%
vs. same field & year
Citations per year
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References
mRNA-based therapeutics — developing a new class of drugs
Nature Reviews Drug Discovery · 2014 · 2,333 citations
RNA-Guided Human Genome Engineering via Cas9
Science · 2013 · 9,293 citations
CRISPR-Cas systems for editing, regulating and targeting genomes
Nature Biotechnology · 2014 · 3,157 citations
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Science · 2012 · 16,935 citations
Multiplex Genome Engineering Using CRISPR/Cas Systems
Science · 2013 · 15,534 citations
Biomolecular coronas provide the biological identity of nanosized materials
Nature Nanotechnology · 2012 · 2,677 citations
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
Cell Reports · 2018 · 810 citations
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