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A Familial Cluster of Infection Associated With the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period

The Journal of Infectious Diseases · 2020 · Vol. 221(11) · pp. 1757–1761

Ping Yu✉Zhu Jiang(Shanghai Municipal Center For Disease Control Prevention)Zhengdong ZhangYingjun Han

Abstract

An ongoing outbreak of pneumonia associated with 2019 novel coronavirus was reported in China. It is unclear whether the virus is infective exists during the incubation period, although person-to-person transmission has been reported elsewhere. We report the epidemiological features of a familial cluster of 4 patients in Shanghai, including an 88-year-old man with limited mobility who was exposed only to asymptomatic family members whose symptoms developed later. The epidemiological evidence has shown possible transmission of 2019 novel coronavirus during the incubation period.

SARS-CoV-2 and COVID-19 Research COVID-19 epidemiological studies COVID-19 Clinical Research StudiesIncubation periodTransmission (telecommunications)IncubationCoronavirusCluster (spacecraft)Coronavirus disease 2019 (COVID-19)VirologyPeriod (music)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreak

MeSH terms

BetacoronavirusCOVID-19SARS-CoV-2AgedAged, 80 and overChinaFamilyFemaleHumansMalePneumonia, ViralFatal OutcomeCoronavirus InfectionsInfectious Disease Incubation PeriodPandemics

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