Association of helicobacter pylori infection in carcinoma stomach and peptic ulcer disease: A cross sectional analytical study

Abstract

Background and Aims: The Helicobacter pylori (H. pylori) prevalence in Asian countries is highly variable. We aimed to determine the current H. pylori prevalence, correlate with gastroduodenal diseases and study gastric cancer incidence in western Odisha.Methods: Out of 3289 patients referred for endoscopy, 2820 eligible patients underwent upper gastrointestinal endoscopy with biopsy and included in the study; H. pylori was considered positive when either of Rapid Urease Test (RUT) or histopathology showed positive result.Results: The H. pylori prevalence was 29.2% in overall distribution, 41.1% in gastritis and or duodenitis, 65.1% in gastric ulcer, 83.3% in duodenal ulcer, 19.2% in gastric polyp and 11.1% in gastric cancer. The H. pylori in fection was significantly associated with gastritis and or duodenitis [P