Comparision of efficacy of labetalol vs nifedipine in pregnancy induced hypertension

Abstract

In pregnancy, if diastolic blood pressure rises above 110mmHg, and does not settle with rest, there is increase in danger to both mother and foetus with potential fatal complication of cerebro vascular accidents, eclampsia and placental abruption in mother and IUGR and increased perinatal mortality in foetus. One hundred and twenty four cases of Pregnancy Induced Hypertension were studied during the period of 2 years at the Department of Obstetrics and Gynaecology, Government General Hospital, a Teaching Hospital attached to Medical College. 30.65% of Labetalol group were preterm deliveries where as 43.55% of Nifedipine group delivered preterm. Intra Uterine Growth Retardation was 6.45% with Labetalol and 4.83% with Nifedipine. Over all Perinatal Mortality was 11.29% with Labetalol and 19.35% with Nifedipine.