A histopathological analysis of colorectal cancer

Abstract

Background: Carcinoma of the colon or rectum is a common and lethal disease. The present study was conducted to assess histopathology of colorectal cancer. Materials & Methods: The present study was conducted on 112 rectum specimens. Tumor invasion depth, surgical margin status, lymph vascular/perineal invasion, presence/absence of metastatic lymph nodes, neoadjuvant therapy, and regression rates were assessed. Results: Out of 112 specimens, 64 were of males and 48 of females. There was mild treatment response in 21, moderate in 15, high in 14 and complete regression in 10 cases. Tumor type was adenocarcinoma in 76, mucinous adenocarcinoma in 23, malign melanoma in 6, signet ring cell carcinoma in 4, and gastrointestinal stromal tumor in 2 and endometriosis in 1 case. Conclusion: Authors found that histopathology revealed that maximum cases were of adenocarcinoma followed by mucinous adenocarcinoma.