A study to compare the maternal and fetal effects with the use of tramadol as an analgesic during labour

Abstract

Perception of pain during the first stage of labour begins with nociceptive stimuli arising in the mechanical and chemoreceptors in the uterus and cervix.21High threshold mechanoreceptors get stimulated due to intense pressure generated during contractions of the uterus.22Myocellular injury due to repeated contractions in later stages, release bradykinin, histamine, serotonin, acetylcholine and potassium ions which activate chemical nociceptors. All patients with Term pregnancy (gestational age between 37- 42wks) without cephalopelvic disproportion, in active labour, admitted to the Labour Room of Medical College and Research Foundation. Among the intervention group 94.28% (33 babies) had no depression, 5.7% (2 babies) had mild depression and none of the babies had severe depression at 1 minute. In the control group 88.5% (31 babies) had no depression, 11.4% (4 babies) had mild depression and none of the babies had severe depression at 1 minute. p> 0.05, statistically not significant.