Serum triglyceride level in early pregnancy as a predictive marker for risk of pre eclampsia; A prospective clinical controlled study

Abstract

Pregnancy is a hyperlipidemic state as atherosclerosis, due to hormonal changes. To study aimed to investigate the relationship between early pregnancy serum triglyceride concentration and the risk of pre-eclampsia. 270 cases were selected from pregnant women 13- 20 weeks of gestational age who attended outpatient antenatal clinic. All routine investigations with a special investigation of serum lipid profile including triglyceride level were done. The mean triglyceride level was found to be 153.95±23.52 mg/dl in the control group and 205.25±42.48 mg/dl in the study group. It was 198.99±36.12 mg/dl in mild PET group and 220.35±53.13 mg/dl in severe PET group. The mean triglyceride levels in the control group were found to be significantly lower as compared to that in the study group (p<0.001) In the present study we have observed that maternal dyslipidemia in the early second trimester is associated with an increased risk of developing pre eclampsia.