Effect of autologous bone marrow application in deep burn management: A quasi experimental study

Abstract

Aim: To study effect and efficacy of bone marrow therapy in burn wound healing. Material and Methods: Two groups of 25 patients each were selected randomly. The patents under study group were treated by debridement followed by autologous bone marrow therapy to wound site whereas patients under control group underwent debridement only. The patients were then followed postoperatively.Results: Post operatively the patients in study group experienced less pain. Biopsy from wound bed showed average improved fibroblast, macrophage, neovascularisation, and less necrosis per HPF in study group in comparison with that of control group. Seropurulent discharge in control group was observed in 72% cases but in study group it was 28%. Contractures in case group were seen in 32% cases but in control group it was 64%.Conclusion: Bone marrow cell therapy is a novel method in deep burn wound management in enhancing wound healing and minimizing complication.