Comparison of intubating conditions and haemodynamic changes using Vecuronium and Rocuronium bromide for laryngoscopy

Abstract

The use of muscle relaxant for intubation has become an important aspect of modern anaesthesia. Different new nondepolarizing drugs are in use for the same purpose. Aims and Objectives: To compare the effect on intubating conditions and haemodynamic changes using Vecuronium and Rocuronium bromide for laryngoscopy. Methodology: Present randomized controlled study was conducted on 60 patients, between 18 - 60 years of age and belonging to ASA grade I & II who were scheduled for various elective surgeries under general anaesthesia. These patients were randomly allocated into two groups of thirty each. All were premedicated and induced with Inj. Fentanyl and Inj. Propofol. After induction tracheal intubation was facilitated by giving either Inj. Rocuronium 0.6 mg/kg or Inj. Vecuronium 0.1 mg/kg to patients of Group A and Group B respectively. Anaesthesia was maintained on N2O (66.6%) and O2 (33.3%) mixture Analgesics, and either Vecuronium or Rocuronium as muscle relaxant with Sevoflurane. Conclusion: There was no difference in intubating conditions and haemodynamic response between Rocuronium and Vecuronium.