Evaluation of intrathecal neostigmine methylsulphate in different doses added to hyperbaric bupivacaine hydrochloride for postoperative analgesia

Abstract

Pain is a natural protective gift but postoperative pain or its abnormal persistence, has a lot of harmful effects. Postoperative pain is associated with delayed recovery from surgery, hypoventilation and its consequences, delayed ambulation with increased thromboembolic phenomenon, increased sympathetic stimulation with consequent tachycardia, hypertension and increased cardiac work load. Poorly relieved and prolonged pain may produce negative physical and psychological effects leading to sleeplessness, depression and psychosomatic changes. Hence this study is undertaken to evaluate Inj. neostigmine methylsulphate as spinal additive to evaluate their feasibility for postoperative pain relief.Objective 1. Comparison of postoperative analgesia-duration and quality 2. Postoperative vitals monitoring 3. Assessment for need of analgesic, if any 4. Occurrence of side effects if any.