Evaluation of antipyretic, anti-inflammatory and analgesic activities of various leaf extracts of Kigelia africana

Abstract

Present investigation was done on 50 Albino Wistar rats of either sex. Various extracts of Kigelia africana i.e aqueous, alcoholic, acetone and chloroform were evaluated for antipyretic property, anti-inflammatory activity using carrageenan induced paw edema and analgesic activity by tail flick method. Alcoholic extract @ 50 mg/kg showed decrease in temperature after one hour. Aqueous extract @ 100 mg/kg and alcoholic extract @ 50 mg/kg showed significant anti-inflammatory activity whereas significant analgesic activity was shown by aqueous and alcoholic group.