A comparative study on anthelmintic activity of various solvent extracts of Clavaria rosea

Abstract

Helminths are the most common infections in man, affecting a large proportion of the world’s population. The study includes, different solvent (Petroleum ether, chloroform, methanol and aqueous) extracts of the fruiting body of Clavaria rosea had been evaluated separately for anthelmintic activity on adult Indian earth worms, namely Pheretima posthuma. Three concentrations (25, 50 and 100 mg/ml) of various extracts were tested and results were expressed in terms of time for paralysis and the time for death of the worms. The results revealed that the petroleum ether and chloroform extract showed excellent anthelmintic activity at a concentration level of 50 and 100 mg/ml on time taken for paralysis (31 min, 34.16 min and 39.66 min, 40.66 min) and death (70.5 min, 98.5 min and 91.16 min, 114.83 min) of the worms. Activities on further comparison with the standard drug Piperazine citrate (10 mg/ml), the petroleum ether extract showed a significant effect as compared to other extracts