Disrupting Action of Cypermethrin on Thyroid and Cortisol Hormones in The Serum of Cyprinus carpio

Abstract

Through static bioassays, the LC50 96 hr value of cypermethrin to the fishes was found to be 2.0/ppm. Then a sublethal concentration (0.2ppm) was used for assaying chronic toxicity for 4weeks. The blood was collected from the test fishes at intervals (day 4, 7, 14, 21, and 28) for hormonal assays. The pesticide was found to decrease the T3 and T4 levels in the serum of the fishes where as TSH and cortical levels increased. This would affect the regulation of glycogen, cell respiration, antioxidant system, excitability of nervous and muscles and hyperglycemia by the way of breaking down of breaking down of proteins.