Antibiotic susceptibility Pattrens of Pseudomonas aeruginosa in tertiary care hospital

Abstract

Pseudomonas aeruginosa is a leading cause of nosocomial infections. Antibiotic susceptibility patterns of Pseudomonas aeruginosa varied markedly with the antibiotic tested. In this study a total of 40 clinical specimens were investigated, 10 were from females and 30 for males. Most of them belonged to the age group 10-60 years. Urine and blood were the more noticeable sources of specimens of Pseudomonas aeruginosa. Most isolates of Pseudomonas aeruginosa showed maximum resistance to Azithromycin (90%) and Oxacillin (75%), they showed less resistance to Cefoperazone+ Sulbactam (10%) and Imipenam (25%). All isolates were sensitive to the Amikacin, Ofloxacin and Tobramycin. Present study shows the occurrence of resistance and sensitivity to various anti-pseudomonal agents. Cefoperazone + Sulbactam were the only anti-pseudomonal drug against the Pseudomonas aeruginosa was fully sensitive. We recommend a more limited and a more rational use of this drug in this hospital setup. Amikacin and Imipenam are the choice drugs for optimal management of infections caused by Pseudomonas aeruginosa.