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DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput

Nature Methods · 2019 · Vol. 17(1) · pp. 41–44
Vadim DemichevChristoph B. MessnerSpyros I. VernardisKathryn S. LilleyMarkus Ralser
Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and ApplicationsMachine Learning in BioinformaticsDeep learningComputer scienceProteomeThroughputArtificial neural networkSoftwareDeep neural networksProteomicsArtificial intelligenceIdentification (biology)

MeSH terms

Zea maysHeLa CellsHumansSoftwareSpecies SpecificityMass SpectrometryNeural Networks, ComputerProteomeProteomicsHigh-Throughput Screening Assays

Funding

  • Biotechnology and Biological Sciences Research Council
Citations
3,095
FWCI
48.00
field-weighted impact
References
32
Percentile
100%
vs. same field & year
Citations per year
References
A cross-platform toolkit for mass spectrometry and proteomics
Nature Biotechnology · 2012 · 4,194 citations
A Direct Approach to False Discovery Rates
Journal of the Royal Statistical Society Series B (Statistical Methodology) · 2002 · 5,723 citations
UniProt: the Universal Protein knowledgebase
Nucleic Acids Research · 2003 · 7,806 citations
Deep learning
Nature · 2015 · 79,164 citations
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