Efficacy of single dose of zoledronic acid in treating post-menopausal osteoporosis

Abstract

 The purpose of this study is to analyse the effect of single dose of zoledronic acid in treating post-menopausal osteoporosis.Aim of the study To show the significance increase in bmd with zoledronic acid infusion in single dose. Materials Study design - prospective study. Study population - patients attending opd in department of orthopaedics with osteoporosis evaluated by bone mineral density (bmd) scan in govt. kilpaukmedical college hospital. Duration of study – 1 year  After patients were screened with peripheral BMD densitometry patient were selected then they were subjected to do bmd dexa scan to confirm osteoporosis. Those who were in osteoporotic group were included in our study. Method After patient is evaluated, they were instructed to drink 500ml-1000ml of water for hydration.  Then single dose of Zoledronic acid in 100 ml of Normal saline was infused intravenously over 15 mins.  Patient were observed for two hours then were discharged with prophylactic Paracetamol tablets.