Dermatofibrosarcoma protuberans: A clinical presentation and a surgical treatment

Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare nosological entity from the group of soft tissue sarcomas. The etiology of the disease remains unclear. The neoplasm may start growing de novo over healthy skin or as a result of a local chronic trauma, radiation therapy or thermal scar. It affects more commonly middle aged patients with a clear male prevalence. Once developed, the tumor progresses slowly with an indolent growth pattern and might be wrongly taken as a benign neoplasm. However, DFSP has a high local recurrence level and intermediate metastatic activity reported. Surgical excision of the tumor is the most effective treatment method. In the following we present clinical case reports of patients with DFSP.