Predictive value of hyperbilirubinemia, platelet distribution width and mean platelet volume in acute appendicitis and its complications

Abstract

Background: Acute appendicitis is the most common abdominal emergency and its diagnosis and assessment of its severity remains challenging in many cases. This study aims at assessing the predictive value and credibility of elevated bilirubin, Platelet Distribution Width (PDW) and Mean Platelet Volume (MPV) as a diagnostic marker for acute appendicitis and its complications. Methods: A prospective study of 150 patients, who underwent open or laparoscopic appendectomy were included in the study. Diagnosis was based on histopathological report of surgical specimen. Patients total serum bilirubin, PDW and MPV were analysed. Receiver operating characteristic curves were used assess these indices.Results: The mean value of bilirubin and PDW was higher and for MPV was lower in uncomplicated and complicated acute appendicitis (p