Effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain

Abstract

Background: Pain is defined as "unpleasant sensory and sensory experience'', associated with actual or potential tissue damage or described in terms of such damage Objective: To assess the effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain. Patients and Method: An experimental design was made of a controlled clinical trial type, in patients scheduled for lower abdomen surgery or lower extremities. A sample of 60 patients was studied during the period from October 1 to December 15, 2018, who agreed to participate in the study through of signing consent under information. Results: It was observed that the time of the rescue analgesia was prolonged in more than 120 min in the case of dexmedetomidine when compared with bupivacaine (p<0.0001); also VAS scores at the time of analgesia rescue for the group with dexmedetomidine were 3.71 1.27 and in the bupivacaine group of 5.7 1.59, the difference of two points of the VAS (p = <0.001) was significant, which demonstrates that dexmedetomidine is effective for prolong postoperative analgesia and decrease the analgesia requirements Conclusions: Dexmedetomidine at a dose of 5 g associated with bupivacaine administered intrathecally is more Effective in postoperative analgesia compared with this substance alone in abdominal surgery inferior and lower extremities.