The effect of standard treatment modalities on clinical and ovarian parameters in polycystic ovarian syndrome

Abstract

Background: Polycystic Ovarian Syndrome is one of the most common endocrinopathy affecting women of reproductive age group worldwide. The aim of the present study was to find out the effects of standard treatment modalities on Clinical and Ovarian Parameters of PCOS patients attending the Gynaecology OPD of a tertiary care hospital in eastern India.Material and Method: A total of 162 patients were recruited during January 2017 to October 2018 to assess the effects of standard treatment modalities on Clinical and Ovarian Parameters in PCOS patients. The selected patients were divided in two groups A and B based on the clinician’s assessment with respect to the patient profile. Group A received lifestyle intervention plus metformin and Group B received lifestyle intervention plus Oral Contraceptive Pill. 24 patients were loss to follow up. Result: In our study, Group A showed significant reduction in weight and BMI and also improvement in the menstrual symptoms. Group B also showed improvement in the menstrual symptoms but there was a significant increment in the weight and BMI.Conclusion: In the study Group A was found to be more effective in reducing the body weight and BMI while Group B was more effective in reducing the prevalence of USG features suggestive of PCOS. Both the treatment modalities improved the menstrual symptoms and LH: FSH.