A clinicopathological study of neoplastic urinary bladder lesions with special emphasis on the role of urine sediment cytology in their diagnoses

Abstract

Introduction: Neoplastic lesions of the urinary bladder constitute a diverse group of lesions. Bladder cancer is the 7th most common cancer worldwide. The present study is undertaken to study the spectrum of neoplastic bladder lesions and analyze their patterns with clinical features and urine sediment cytology. Materials and Methods: 82 cases of neoplastic bladder lesions were categorized according to WHO classification (2016) and were correlated with demographic variables and clinical variables. In prospective cases urine sediment was analyzed and was correlated with histopathology. Results: Out of 82 cases, majority of cases were infiltrating urothelial carcinoma. Analysis of urine cytology revealed a sensitivity of 86.67%, specificity of 83.3%, positive predictive of 92.86% and negative predictive value of 71.43%. Conclusion: Neoplasms of urinary bladder are diverse in their presentation with urine sediment cytology proving to be a valuable adjunct in early diagnosis and treatment.