Histomorphological and sociodemographic profile of lesions of uterine cervix: A study of 279 cases

Abstract

Background: The major bulk of histopathological specimens are the gynecological specimens consisting of hysterectomies or biopsies of cervix. Routine histopathological evaluation of suspicious lesions can lead to early detection of cancerous lesions. Objective: All specimens were studied histologically and a diagnosis was made. Sociodemographic profile of neoplastic and non-neoplastic lesions was compared using chi-square test. Material and Methods: The study consisted of 279 cases of uterine cervix that were submitted for histopathological evaluation. Result: Benign lesions constituted the major bulk (75.6%) followed by malignant lesions (21.5%) and premalignant lesions (2.87%). The most common benign lesion was chronic cervicitis (33.69%) and most common malignant lesion was keratinizing squamous cell carcinoma (10.39%). Chi square test revealed significant association of malignancy with tobacco use, multiparity and marriage before 18 years. Conclusion: Screening of sexually active females along with awareness against causal factors might help in reducing cervical malignancies.