to determine analgesic efficacy of intra‑articular morphine in arthroscopic knee surgeries- A clinical study

Abstract

Background: The present study was conducted to determine analgesic efficacy of intra‑articular morphine in arthroscopic knee surgeries. Materials and methods: The present study was conducted on 52 adult patients aged between 20- 60 years with American Society of Anesthesiologists physical status grade I or II scheduled for diagnostic or therapeutic knee arthroscopic surgery under subarachnoid block. Patients were divided into 2 groups. Group I received 20 ml of 0.25% bupivacaine intra‑articularly with 1mg of morphine and group II received 3 mg of morphine. Post‑operative pain was assessed with 10‑point VAS, which was recorded after 1, 2, 6, 12 and 24 h after surgery. Results: Out of 52 patients, males were 32 and females were 20. VAS at 1 hour in group I was 4.5 and in group II was 3.2, at 2 hours was 4 in group I and 2. In group II, at 6 hours was 3.5 in group I and 1 in group II, at 12 was 2.5 in group I and 0 in group II, at 24 hours was 1.2 in group I and 0 in group II. The difference was significant (P