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ModelTest-NG: A New and Scalable Tool for the Selection of DNA and Protein Evolutionary Models

Molecular Biology and Evolution · 2019 · Vol. 37(1) · pp. 291–294

Diego Darriba✉(Universidade da Coruña)David Posada(Galicia Sur Biomedical Foundation)Alexey M. Kozlov(Heidelberg Institute for Theoretical Studies)Alexandros Stamatakis(Karlsruhe Institute of Technology)Benoît Morel(Heidelberg Institute for Theoretical Studies)Tomáš Flouri(University College London)

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Abstract

ModelTest-NG is a reimplementation from scratch of jModelTest and ProtTest, two popular tools for selecting the best-fit nucleotide and amino acid substitution models, respectively. ModelTest-NG is one to two orders of magnitude faster than jModelTest and ProtTest but equally accurate and introduces several new features, such as ascertainment bias correction, mixture, and free-rate models, or the automatic processing of single partitions. ModelTest-NG is available under a GNU GPL3 license at https://github.com/ddarriba/modeltest , last accessed September 2, 2019.

Genomics and Phylogenetic Studies RNA and protein synthesis mechanisms Machine Learning in BioinformaticsBiologyScalabilitySubstitution (logic)Selection (genetic algorithm)Protein evolutionComputational biologyScratchGeneticsComputer scienceArtificial intelligence