Maternal tetrahydrofolate reductase gene mutation in patients with missed abortion

Abstract

Background: missed abortion is a common problem, thrombophilia is a common cause of missed abortion either recurrent or not Aim of the work: to correlate presence of MTHFR gene mutation in patients with missed abortion Patients and methods: the study included 200 patients divided into 2 groups; study group included 100 patients with history of missed abortion, and control group included 100 case with no history of missed abortion. Results: of 200 patients only 44 was having MTHFR gene mutation, 34 of them was present in case group while 10 only in control group. Conclusions: MTHFR gene mutation is acommon cause of missed abortion either recurrent or not