Host factors induces immunomodulator effect on pathogenicity of Tilletia indica in wheat

Abstract

Wheat (Triticum aestivum L.) is one of the most important staple foods of the India or even in world. The food grain production of wheat is affected by many more diseases however; the Karnal Bunt (KB) disease is an important disease and caused by Tilletia indica. In this study we have taken three important monosporidial strains of Tilletia indica such as KB3, JKmsb and KBPN6 and they can easily differentiate by each other by morphological variation. Host factor(s) extracted from wheat spikes are heat labile, comprised with multiple components which produce nutritional as well as hormonal effects on the pathogen. It is quite evident that hrost factor(s) trigger the MAP kinases machinery in order to provide signal for induced mycelination, formation and alteration of genetic and surface properties. However it is not clear how the pahtogenisity induces by Tilletia indica in wheat. Here we have shown that host factor(s) treatment induces the pathogenesis of Tilletia indica in wheat by altering the expression pattern of immunodominant proteins. We also observed the time kinetics variation of protein expression in the presence of host factors. Our this study alteration of protein expression pattern in the presence of host factors opens up a possibility of understanding the onset of disease in more detail and that might be helpful to manage the Karnal bunt disease of wheat.