Elevated serum iron levels in pregnant women with preeclampsia

Abstract

Background: Pre-eclampsia is one of the common medical complications that happened during pregnancy, it affecting 5% to 10% of all pregnancies. It is best termed as a pregnancy specific syndrome of reduced organ perfusion secondary to vasospasm and endothelial activation, characterized by hypertension and proteinuira that may lead to multisystem involvement including renal, hematological, hepatic and cerebral impairment.Objective: To assess the elevated serum iron levels in pregnant women with preeclampsia.Patients and method: A case control study conducted in 2 hospitals in Baghdad city (Al-Immamain Al-Khadimain Medical City, and Abugraib general hospital) in one year duration in the period from the 1st of Jan 2017 to the end of Dec 2017, in which 176 women were enrolled in the current study.Results: The mean age of the PE group was (30.2±7) years, (28.4±5) years for control group, with no significant association. Highly significant associations were found between case and control groups regarding; gestational age, mean arterial blood pressure, weight of fetus and premature baby (p value <0.001). Highly significant increase were found in PE patients than healthy patients among serum iron and serum ferritin (P<0.001).Conclusion: Serum iron level was increased in pregnant patients with preeclampsia.