Assessment of in vitro antioxidant activity study of polydatin

Abstract

Polydatin is a monocrystalline segregated from polygonum cuspidatum sieb et zucc. Polydatin also named piceid (3Iµ4'Iµ5-trihydroxystilbene-3-β-D glucosideIµPD).Polydatin is also detected in grapes, peanut, hopcons, redwines and hop pellets. Umpteen pharmacological exploration of polydatin mainly focus on cardiovascular effects, neuroprotection, immunoregulatory effects, anti –inflammatory, anti-oxidation, anti-tumor [1]. In our present study was to evaluate the antioxidant activity of polydatin. Antioxidant activity of polydatin determined by four different invitromethods.Theyare1,1diphenyl-2-picrylhydrazlradical(DPPHI‡),2,2-azino-bis-(3-ethylbenzothiazoline-6-sulphonate) radical cation (ABTSI‡),hydroxyl radical (OHI‡) and superoxide anion radical (Oâ‚‚I‡O¾) established the free radical scavenging and antioxidant activity of polydatin [2].