A comparison of liver enzymes, bilirubin and uric acid in preeclampsia, eclampsia and normotensive subjects

Abstract

Introduction: Liver enzymes (AST, ALT, ALP), Bilirubin and uric acid is important biochemical parameters in diagnosis and prognosis of preeclampsia, eclampsia. Present was an attempt to analysed three biochemical parameters of patients and compared with normal pregnant women with normal pregnancy.Materials and Methods: Two hundred subjects were studied among 100 (pregnant women) of preeclampsia and eclampsia and 100 of without complicated pregnancy respectively. Serum AST, ALT, ALP, bilirubin and uric acid determined by commercial kit method. Ethical permission were taken from institution ethical committee.Results: Level of AST, ALT, and ALP were found to be significant in our study when compared with control subjects. Bilirubin and uric acid were insignificant.Conclusion: Present study demonstrates that levels of AST, ALT, and ALP impairment found to be in preeclampsia, eclampsia patients as compared to normal pregnant women.