Evaluation of alteration of glomerular filtration rate in operated kidney after percutaneous nephrolithotomy operation

Abstract

Background: Percutaneous Nephrolithotomy (PCNL) is advanced minimally invasive endoscopic procedure for management of renal stones. There are limited studies showing early changes of renal function following PCNL. Knowledge of the changes of renal function after PCNL may act as a guide during postoperative follow-up, especially those at risk.Methods: From 1st November 2016 to 30th October 2018, patients were subjected to PCNL under general anaesthesia. A preoperative 99 m Tc DTPA renal scan was performed & repeated on 3rd & 14th post-operative day. Results: Total 102 patients were divided into 19-32, 33-46 and 47-60 years group. At post-operative day-3 GFR of operated kidney reduced significantly in all 3 age groups (p=.05). Conclusions: Nephrotoxic drugs, contrast agents, ESWL etc. has negative influence on renal function. These should be avoided to prevent further trauma of operated kidney in early post-operative period.