Homoeopathic pathogeneses of dioscorea villosa and the role of dysregulated cholesterol metabolism by the action of diosgenin: A review

Abstract

Background: Dioscorea villosa (Dioscorea) is one of the important homoeopathic medicines for gastro-intestinal, sexual, cardiovascular, peripheral inflammatory or neurological affections. Diosgenin is the primary active ingredient of Dioscorea which is responsible for all possible revealed actions of this plant. Objective: To know background patho-physiology for development of homoeopathic pathogeneses of Dioscorea.Method & Result: Homoeopathic pathogeneses of Dioscorea, have been collected from 11 homoeopathic books and 1article. A comprehensive online search on different actions of diosgenin and dioscorea itself (18 research and 5 reviews), for hyperactivity of cholesterol as well as lipid metabolism in different patho-physiological fields (14 research and 17 reviews), along with other related articles have been assessed by using PubMed and other sources and appraised according to their research outcome.Conclusion: By the action of diosgenin, altered or dysregulated cholesterol metabolism might have a background patho-physiological role to develop homoeopathic pathogeneses of Dioscorea.