Role of calcium dobesilate in management of internal haemorrhoid: An interventional study

Abstract

Introduction: Internal Haemorrhoids are symptomatic anal cushions. These anal cushions are normal, vascular tissue within the submucosa located in the anal canal. Caudal displacement, structural distortions and mucosal trauma of anal cushions leads to the symptoms of this disease. A randomised, double blind controlled study was conducted to investigate the efficacy of oral and local application of calcium dobesilate in management of acute attacks of internal haemorrhoid. Methods: 40 patients of 1st and 2nd degree internal haemorrhoid were treated with calcium dobesilate along with high fibre diet and stool softeners for 4 weeks, while 40 patients received only high fibre diet and stool softeners to serve as control.patients were kept on followup and both symptoms and anoscopic inflammation were scored on a scale from 0 to 2 before and after 4 weeks of treatment. Results: With calcium dobesilate oral and local therapy for 4 weeks, a success rate of 77.5% with cessation of bleeding plus lack of severe anitis on anoscopic examination was achieved and the reduction of symotoms and anoscopic inflammation were also significantly better than those with diet therapy only. Conclusion: In addition to dietary management and proper bowel habits, oral and local supplementation of Calcium dobesilate provides an effective and fast and relief from acute symptoms of 1st and 2nd degree haemorrhoid. This symptomatic relief is associated with significant improvement in anoscopically observed inflammation.