articleTop 10% cited
Low rectal cancer
Diseases of the Colon & Rectum · 1998 · Vol. 41(9) · pp. 1087–1096
Angelita Habr‐Gama✉(Color (United States))Pedro Marcos Santinho Bueno de Souza(Color (United States))Ulysses Ribeiro(Color (United States))Wladimir Nadalin(Color (United States))Rene Claúdio Gansl(Color (United States))Afonso Henrique Silva e Sousa(Color (United States))Fábio Guilherme Campos(Color (United States))Joaquim Gama‐Rodrigues(Color (United States))
Abstract
Combined up-front chemoradiotherapy was associated with tolerable and acceptable side effects. A significant number of patients had complete disappearance of their tumors (30.5 percent) within a median follow-up of 36 months. This regimen spared 26.2 percent of patients from surgical treatment and allowed sphincter-saving management in 38.1 percent of patients who may have required abdominoperineal resection. Preliminary results of this trial suggests a reduction in the number of local recurrences and reinforces the concept that infiltrative low rectal cancer may be initially treated by chemoradiotherapy.
Colorectal Cancer Surgical TreatmentsColorectal and Anal CarcinomasGastric Cancer Management and OutcomesMedicineRegimenRadiation therapySurgeryBiopsyChemotherapyColoanal anastomosisFluorouracilColorectal cancerRadiology
MeSH terms
AdenocarcinomaAdultAgedAged, 80 and overAnastomosis, SurgicalAntineoplastic Combined Chemotherapy ProtocolsLeucovorinCombined Modality TherapyFemaleFluorouracilFollow-Up StudiesHumansMaleMiddle AgedProspective Studies
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326
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33
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