Single donor Plateletpheresis and its adverse donor reactions observed in central India

Abstract

Background: Plateletpheresis is a sophisticated technology by which blood is processed by an apheresis machine that uses the principal of centrifugation to extract a desired component of the blood and returns the rest of the components to the donor in real time. Apheresis procedures are usually well tolerated, but adverse events in donor do occur in a few cases. Aim and Objective: To study the Adversed donor reactions observed during single donor Plateletpheresis. Material and Method: A retrospective, observational, study of 110 healthy voluntary donors after taking informed written consent.Results: It was observed that out of 110 Single donor Plateletpheresis only five had adverse reactions (4.54 %).Two donors had tingling sensation in perioral area. Two had nausea and vomiting i.e. vasovagal reaction of mild intensity and only one with hematoma formation.Conclusion: Apheresis performed on cell separator are safe and well tolerated having less adverse reactions however these reactions are relatively mild and easily treated.