Immunohistochemical study for typing of soft tissue neoplasms: Experience at a tertiary care institute

Abstract

Immunohistochemistry (IHC) plays an important role in soft tissue tumours diagnosis. It is important that immunohistochemical evaluation must be employed with the clinical picture, the morphology and when necessary, other ancillary techniques such as molecular genetics and cytogenetic. The present study was conducted to include the morphological typing of the soft tissue tumours with the help of Immunohistochemistry markers. Immunohistochemistry provides an additional tool by which one can analyse poorly differentiated sarcomas and characterize them. Its specificity, sensitivity, cost effectiveness and applicability to routinely processed material, clearly make it an essential part of diagnostic pathological studies for soft tissue tumors. Also an attempt to categorise the soft tissue neoplasm according to World Health Organization [WHO] 2013 classification.